File Selection

Details

Please select files for upload. (1MB max). For demonstration purposes, we have added a sample text file that you can select using the checkbox below. It is a text file containing the lyrics of the song "Bohemian Rhapsody" by Queen.

Bohemian_Rhapsody_Lyrics.txt

Data Encoding

Details

Encoding Method:
Currently, we support six encoding methods: (i) MaxDensity (exhibits the highest density of information - two bits in every nucleotide) and (ii) NoHomopolymer (designed to prevent homopolymers in the DNA strand) are based on a de-novo synthesis approach. (iii) LinearChain (based on building DNA strands by hybridising and ligating oligos in a linear order, see [2]), and (iv) LinearBinomial (based on the same assembly strategy but encodes data in a combinatorial manner, see[1,2]). (v) PolyChain (based on building DNA strands by hybridising and ligating oligos in a positional order, see [2]), and (vi) PolyBinomial (based on the same assembly strategy but encodes data in a combinatorial manner, see[1,2]).

References

[1] Preuss, I., Rosenberg, M., Yakhini, Z. et al. Efficient DNA-based data storage using shortmer combinatorial encoding. Sci Rep 14, 7731 (2024). DOI: https://doi.org/10.1038/
[2] Wernhart, K., Schroeder, F., Barisic, I., 2025. Example Title for Another Paper. Journal of Example Research, 15(3), pp.789-1011. DOI: 10.5678/example.doi here
The manuscript can be downloaded here.

Select an encoding method:

Codeword Length: DNA Barcode Length: Codeword Maxlength Positions:

Codeword Length: DNA Barcode Length: Codeword Maxlength Positions: Library:

DNA Barcode Length: Codeword Maxlength Positions: Sigma: Library:

DNA Barcode Length: Codeword Maxlength Positions: Library:

DNA Barcode Length: Codeword Maxlength Positions: Sigma: Library:

Error Correction

Details

Outer error Correction:
Outer error correction adds redundant information to every codeword to enable the correction of errors in the data, like substitutions, insertions, and deletions, see [1]. Currently, only the Reed Solomon code is supported but the percentage of redundancy can be adjusted by the user.

Inner error Correction:
The inner error correction scheme is applied to the data after the outer error correction scheme is applied and adds redundant codewords to make it more resilient against the loss of entire codewords. Currently, we support the LT code [2] only, where the user can specify the percentage of additional codewords. Block-by-block assembly based DNA encoding methods have an intrinsic error correction, since sequencing reads can be aligned to the oligo library used for assembly. This allows to recover lost data as long as enough correct oligos are present in the sequencing reads. Still, in most cases it is beneficial to add (at least) inner error correction.

References

[1] Wesley, W., Weldon, E., 1982. Error-Correcting Codes. (2nd edition) MIT Press, Cambridge, MA.
Luby, Michael. (2002). LT codes. Annual Symposium on Foundations of Computer Science - Proceedings. 271-. DOI: 10.1109/SFCS.2002.1181950.
The manuscript can be downloaded here.

Select inner error correction:

Percent of symbols: Index carry length (default: 15% of codeword length): LT code header (default: 15% of codeword length):

Select outer error correction:

Percentage: